Quantitation and Mass Spectrometric Data of Drugs and Isotopically Labeled Analogs

book24h

Power User
LV
5
 
Csatlakozás
2024.09.10.
Üzenetek
43,663
Reakció pontszám
8
Díjak
5
Kor
37
e7b2f516dacfa487997940f12d5a9e8e.webp

Free Download Dennis V. Canfield, Sheng-Meng Wang, "Quantitation and Mass Spectrometric Data of Drugs and Isotopically Labeled Analogs"
English | 2009 | pages: 474 | ISBN: 1420094971 | PDF | 9,8 mb
The analysis of drugs and their metabolites in biological media are now expected to routinely achieve ± 20% accuracy in the ng/mL concentration level. Therefore, the availability and the selection of quality ion-pairs designating the analytes and their isotopically labeled analogs (ILAs) are important considerations in achieving the accuracy of quantitation results. Assisting scientists with this process, Quantitation and Mass Spectrometric Data of Drugs and Isotopically Labeled Analogs provides an extremely valuable reference for labs involved in the analysis of therapeutic and abused drugs.

Part One of this comprehensive volume illustrates approaches, mechanisms, and challenges pertaining to the use of isotopic analogs as internal standards for drug quantitation. The second section is a systematic compilation of full-scan mass spectra of drugs and their analogs, as parent compounds and as derivatives resulting from various chemical derivatization approaches, commonly encountered in today's labs. Based on the mass spectra data presented in the second section, Part Three provides corresponding tables of ion-pairs which can potentially be adapted to designate the drugs and their isotopic analogs in the analytical processes. Relative quality of these ion-pairs (cross-contribution to the intensity of these ions by their isotopic analogs) is included in these tables.
With more than 1500 full-scan mass spectra and quick access data tables, this text represents the authors' years of work compiling mass spectra of the many chemical derivatization forms of drugs, their metabolites, and their isotopically labeled counterparts. The unparalleled scope of this compilation makes it a critical one-stop reference for those involved in drug analyses of biological specimens and interpretation of results.

Buy Premium From My Links To Get Resumable Support,Max Speed & Support Me
Code:
            
                
                
                    
                   
                    A kód megtekintéséhez jelentkezz be.
					Please log in to view the code.
                
            
        
Links are Interchangeable - Single Extraction
 
Top Alul